Luciana Giardino · 
| Address: |
DIMORFIPA, University of Bologna Via Tolara di Sopra, 50 40064 Ozzano Emilia (BO) |
|
Tel: Fax: |
+39 051 2097945 +39 051 2097953 |
Skills and competences
Animal models to develop neurodegenerative pathology
- animal models for multiple sclerosis:
- encephalomyelitis in rat, mouse and primate marmoset to study remyelination enhancing therapies
- encephalomyelitis in rat, mouse and primate marmoset to study grey matter pathology
- animal models for pain:
- acute inflammatory pain: carragenin, CFA injection
- chronic neuropathic pain: axotomy, Bennett's ligature
- visceral pain: cystitis
- muscle pain: muscle carragenin injection
- animal models for dementia:
- transgenic Alzheimer mice
- selective cholinergic lesion
- vascular injury (2VO)
- transgenic animals for the study of neurological diseases:
- Breeding, behavioural,morphological and molecular characterization
- microsurgery laboratory:
- minipump implantation (delivery of drugs, growth factor, etc.)
- intraventricular injection
- specific neuroanatomical lesions
Behavioural tests
- learning and memory: Morris Water Maze, contextual fear conditioning (video tracking softwares)
- locomotor activity: activity cage (spontaneous locomotor activity), rotarod (motor-sensory integration)
- pain threshold: thermal stimulation (plantar test), mechanical (algesimeter) and allodynia (electronic von Frey) in free-moving animal; edema measurement (plethysmometry); force intensity (Grasping force meter)
