Roberto Gambari · 
| Address: |
Biochemistry and Molecular Biology Department, University of Ferrara Via Fossato di Mortara 74 44100 Ferrara |
|
Tel: Fax: |
+39-0532 974443 +39-0532 974500 |
Skills and competences
- Gene expression, sequencing, , transcriptomic, proteomic and secretomic analysis (using micro- and macro-array technology, Bio-plex, 2D electrophoresis)
- Protein-protein, DNA-protein and drugs-DNA interactions (using SPR-based instruments, including BIAcore)
- Validation of peptide nucleic acids (PNAs)- and locked nucleic acids (LNAs)-based molecules
- Development of antisense, triple-helix forming, decoy oligonucleotides for the control of gene expression
- Virtual screening, docking and bioinformatics for the screening of bioactive compounds
- Development of in vitro cellular assays for the development of therapeutic approaches for the treatment of thalassemia, cystic fibrosis, cancer, HIV-1 infection, osteoporosis
- Biological assays using extracts and essential oils from medicinal plants
- Analysis of secretomics of human oocytes and fertilized embryos
- Development of retroviral vectors for gene therapy
- Development of in vivo model system for thalassemia
- Molecular diagnosis of genetic diseases using novel technologies
- Analysis of biocompatibility of materials used for the fabrications of biomedical devices
- Validation of Lab-on-a-chip technologies in the fields of pharmacology, cancer immunotherapy and diagnosis
- Development of cellular biosensors
