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Drug Discovery

Drug Delivery Systems

Medicine manufacturing and quality

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New protocols for somatic stem cells isolation and expansion

Tissue regeneration of skin, cornea, conjunctiva, urethra, oral mucous, heart, brain

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Sequence analysis: databases acquisition and development, database mining, annotation of genome, transcriptome, proteome, metabolome, comparison and integration (comparative genomics)

Signal analysis (functional bioinformatics): genotyping, gene expression, protein expression, metabolic pathways computation and control, classification and prediction service (identification of diagnostic and prognostic markers), pharmacogenomics

Analysis of information related to sequences, structures, signals, samples: network reconstruction, regulatory system analysis, ontology, text-mining

Software development and consulting for clinical and genetic data management (clinical bioinformatics)

Data archiving and management with high availability and security levels of service, in particular for microarray experiments data

Statistical analyses of genetic data

Software development and consulting about business processes in the health and medical areas

Consulting about security criteria of data archives, database organisation and personal data management (DLGS 196/2003)

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Design of cellular biosensors

Cellular biosensor based assay development for biological parameters testing

Biomolecolar interaction testing

Drug-screening

Inflammation studies

Gene expression profiling and genotyping

Pharmacogenetics anf Pharmacogenomics

Applied Bioinformatics

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preclinic study (behavioural, morphologic, biochimic, molecular study), in vitro and in animal models of pathology, molecules and drugs for:

• Alzheimer disease
• Vascular disease
• Parkinson disease
• Cannabis and alcohol overindulgence
• Multiple Sclerosis
• Ataxia
• Acute pain
• Chronic pain
• Acute myocardial infarction
• Pulmonary hypertension
• viral encephalitis
• antiviral assays in vitro and ex vivo
• other models, by pilot study

clinical studies (dosages of biological fluids and tissues):

• beta-amyloid fragments (Mesoscale system)
• tau/Ptau (Mesoscale system)
• other cytokines, by pilot study